NEDD4 Mouse Monoklonale Antilichaam [Kloon ID: LBI5F8]

This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. [provided by RefSeq, Jul 2016]

Carrier-free (BSA/glycerol-free) NEDD4 mouse monoclonal antibody, clone LBI5F8

NEDD4-1; RPF1

Homo sapiens NEDD4 E3 ubiquitin protein ligase (NEDD4), transcript variant 2, mRNA.

4734

P46934

Unconjugated

Endocytosis, Ubiquitin mediated proteolysis

Endocytosis, Ubiquitin mediated proteolysis

WB 1:500

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

NEDD4

https://www.ncbi.nlm.nih.gov/gene/?term=4734

https://www.uniprot.org/uniprot/P46934