Neferine

2292-16-2

(R) -1,2-Dimethoxyaporphine

C10751-10mg

HIV

Microbiology

CN1CCC2=CC (=C (C=C2C1CC3=CC=C (C=C3) OC) OC4=C (C=CC (=C4) CC5C6=CC (=C (C=C6CCN5C) OC) OC) O) OC

C38H44N2O6

Neferine ((R) -1,2-Dimethoxyaporphine), a natural component of Nelumbo nucifera, has antitumor efficiency. Neferine induces apoptosis in renal cancer cells. Neferine prevents autophagy through activation of Akt/mTOR pathway and Nrf2 in muscle cells. Neferine strongly inhibits NF-κB activation. Neferine possesses a number of therapeutic effects such as anti-diabetic, anti-aging, anti-microbial, anti-thrombotic, anti-arrhythmic, anti-inflammatory and even anti-HIV.

2 years -80 in solvent