NEFL-antilichaam

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

4747

P07196

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 400-543 of human NEFL (NP_006149.2) .

Unconjugated

Primary Antibodies

Cell Cycle, Neuroscience, Signal Transduction, Stem Cell

Affinity purification

MCF7

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 72kDa

IgG

NEFL

Neurofilament, light polypeptide

Homo sapiens

NEFL, 68 kDa neurofilament protein, CMT1F, CMT2E, NF68, NF-L, NFL, Neurofilament subunit NF-L

WB, IHC, IF

Liquid