NEP (1-40), N-terminaal ongekapt

NEP (1-40), N-terminal uncapped is a NEP (1-40) analog without the acetylation modification at the N-terminal. NEP (1-40) is a Nogo-66 receptor (NgR) antagonist peptide[1].

12352209

Drug Derivative

Others

COVID-19-immunoregulation

Inflammation/Immunology

98.22

O=C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CCCCN)C(NCC(N[C@@H](C(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H](CC2=CNC=N2)C(N3[C@@H](CCC3)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC6=CC=C(C=C6)O)C(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N

C204H322N56O64

4583.08

[1]Jenna M Ziebell, et al. Nogo Presence Is Inversely Associated With Shifts in Cortical Microglial Morphology Following Experimental Diffuse Brain Injury. Neuroscience. 2017 Sep 17;359:209-223.

Blue Ice

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-P1242B/NEP-1-40-N-terminal-uncapped-SDS-MedChemExpress.pdf

Peptides

No Development Reported