Nephrin (NPHS1) Mouse Monoclonal Antibody [Kloon ID: LBI9D3]

This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.[provided by RefSeq, Oct 2009]

Carrier-free (BSA/glycerol-free) NPHS1 mouse monoclonal antibody, clone LBI9D3

CNF; nephrin; NPHN

Homo sapiens NPHS1 adhesion molecule, nephrin (NPHS1), mRNA.

4868

O60500

Unconjugated

WB 1:500-1000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Transmembrane

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

NPHS1

https://www.ncbi.nlm.nih.gov/gene/?term=4868

https://www.uniprot.org/uniprot/O60500