Neratinib
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Neratinib is a potent, irreversible inhibitor of HER2/ErbB2 receptor tyrosine kinase and EGFR kinase (IC50’s= 59 nM and 92 nM, respectively) . It suppresses receptor autophosphorylation and proliferation, blocks cell-cycle progression and inhibits HER2 signaling in of EGFR-dependent cancer cells and tumor xenograft models.1 Neratinib inhibits proliferation of gefitinib-resistant non-small cell lung cancer cells expressing mutant EGFR.2 Synergizes with dasatinib in HER2-positive cancer cells and xenografts.3 It’s been shown to also inhibit MST1 (IC50 = 37.7 nM) .4
Unconjugated
White solid
-20°C
Beschrijving
Neratinib Beschikbaar in 20 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
Cellubrevin Antibody
MBS9436639-01
0.05 mL
Oxidative Stress Combo Assay Tissue Kit
EA-7008
1 Each
Arachis hypogaea Lectin (PNA) - Biotinylated
21510020-1
5mg
1,4- Dioxane Pure
1041330 500
500 mL
Benzonase ELISA Kit
EG23601S
96 Tests
Not I Restriction Enzyme
B2016623
500 Units
K562-HLA-G0101 Overexpressing Cell Line
RG-1214
5x 10^6
Yeast Poly (A) Polymerase
RNT-006-S
30000 Units
Recent gezochte producten
Cellubrevin Antibody
MBS9436639-01
0.05 mL
Rat Oxidative Stress Primer Library
ROSL-I
1 set
DTNB (Ellman’s) Thiol Oxidative Stress Assay
1021
1 Kit
OSR1 (Oxidative Stress Responsive 1)
MBS616581-01
0.1 mL
Oxidative Stress Combo Assay Cell Kit
EA-7006
1 Each
Oxidative Stress Combo Assay Blood Kit
EA-7007
1 Each
Oxidative Stress Combo Assay Tissue Kit
EA-7008
1 Each
OSR1 (Oxidative Stress Responsive 1)
O8054
100 µL