Nervonzuur-d18

Nervonic acid-d18 (Selacholeic acid-d18) is the deuterium labeled Nervonic acid. Nervonic acid is a monounsaturated fatty acid with oral activity. Nervonic acid exerts anti-inflammatory activity by inhibiting NF-κB signaling. Nervonic acid can be used in the study of neurodegenerative diseases[1][2][3].

Selacholeic acid-d18; cis-15-Tetracosenoic acid-d18

12352211

Endogenous Metabolite; Isotope-Labeled Compounds; NF-κB

Metabolic Enzyme/Protease; NF-κB; Others

Inflammation/Immunology; Neurological Disease

OC(CCCCCCCCCCCCC/C=C(C([2H])(C([2H])(C([2H])(C([2H])(C([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H])[2H])[2H])[2H])[2H])/[2H])=O

C24H28D18O2

384.73

[1]Umemoto H, et al. Protective Effect of Nervonic Acid Against 6-Hydroxydopamine-Induced Oxidative Stress in PC-12 Cells. J Oleo Sci. 2021;70 (1) :95-102.|[2]Hu D, et al. Nervonic acid amends motor disorder in a mouse model of Parkinson's disease. Transl Neurosci. 2022 Apr 20;13 (1) :71.|[3]Yuan SN, et al. Improved colonic inflammation by nervonic acid via inhibition of NF-κB signaling pathway of DSS-induced colitis mice. Phytomedicine. 2023 Apr;112:154702.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W746544/

Isotope-Labeled Compounds

No Development Reported