Neurofilament (NEFL) Mouse Monoclonal Antibody [Kloon ID: LBI2C12]

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]

Carrier-free (BSA/glycerol-free) NEFL mouse monoclonal antibody, clone LBI2C12

CMT1F; CMT2E; CMTDIG; NF-L; NF68; NFL; PPP1R110

Homo sapiens neurofilament light chain (NEFL), mRNA.

4747

P07196

Unconjugated

Amyotrophic lateral sclerosis (ALS)

Amyotrophic lateral sclerosis (ALS)

ELISA 1:5000-10000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, ES Cell Differentiation/IPS

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

NEFL

https://www.ncbi.nlm.nih.gov/gene/?term=4747

https://www.uniprot.org/uniprot/P07196