Neuropeptide AF1

Neuropeptide AF1 is a FMRFamide-like neuropeptide. Neuropeptide AF1 can be isolated from head extracts of the nematode Ascaris suum. Neuropeptide AF1 rapidly and reversibly abolishs slow membrane potential oscillations of identified ventral and dorsal inhibitory motoneurons and selectively reduces their input resistances. Neuropeptide AF1 inhibits locomotory movements in intact Ascaris[1].

130092-56-7

12352209

Others

Others

Neuroscience-Neuromodulation

Neurological Disease

O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CCCNC(N)=N)NC([C@H]([C@@H](C)CC)NC([C@H](CC2=CC=CC=C2)NC([C@H](CCC(O)=O)NC([C@H](CC(N)=O)NC([C@H](CCCCN)N)=O)=O)=O)=O)=O)=O

C45H69N13O10

952.11

[1]Cowden C, et al. AF1, a sequenced bioactive neuropeptide isolated from the nematode Ascaris suum. Neuron. 1989 May;2 (5) :1465-73.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P2135/

Peptides

No Development Reported