Neuroserpin (SERPINI1) Mouse Monoclonal Antibody [Kloon ID: LBI1A5]

This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) SERPINI1 mouse monoclonal antibody, clone LBI1A5

HNS-S1; HNS-S2; neuroserpin; PI12

Homo sapiens serpin family I member 1 (SERPINI1), transcript variant 1, mRNA.

5274

Q99574

Unconjugated

WB 1:2000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Secreted Protein

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

SERPINI1

https://www.ncbi.nlm.nih.gov/gene/?term=5274

https://www.uniprot.org/uniprot/Q99574