NF-kB p65 Antilichaam [8F9G2]

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

5970

Q04206

Human, Mouse, Rat

Recombinant protein of human NF-kB p65

[8F9G2]

Unconjugated

Primary Antibodies

Apoptosis, Cancer, Cell Cycle, Immunology, Neuroscience, Obesity, Signal Transduction, Transcription

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 70kDa

IgG

RELA

Jurkat

HT-29

SGC-7901

NIH/3T3

Mouse liver

V-rel avian reticuloendotheliosis viral oncogene homolog A

Homo sapiens

RELA, p65, NFKB3

WB, IHC, IF, IP

Liquid