NF-kB p65 Antilichaam, KO gevalideerd

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

5970

Q04206

Human, Mouse

A synthetic peptide corresponding to a sequence within amino acids 450-550 of human NF-kB p65 (NP_068810.3) .

Unconjugated

Primary Antibodies

Antibody is Knockout validated.

Apoptosis, Cancer, Cell Cycle, Immunology, Neuroscience, Obesity, Signal Transduction, Transcription, Inflammasomes

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 65kDa

IgG

WB: 1:500 - 1:1000

RELA

V-rel avian reticuloendotheliosis viral oncogene homolog A

Homo sapiens

RELA, p65, NFKB3

WB

Liquid