NFATC2 Antilichaam

This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR) . This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.

4773

Q13469

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NFATC2 (NP_775114.1) .

Unconjugated

Primary Antibodies

Cancer, Immunology, Signal Transduction, Transcription

Affinity purification

Jurkat

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 130kDa

IgG

WB: 1:500 - 1:2000

NFATC2

Mouse thymus

Mouse spleen

Rat liver

Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

Homo sapiens

Nuclear Factor of Activated T Cells; Cytoplasmic 2; NF-ATc2; NF-ATp

WB

Liquid