NFE2L2 Antibody - C-terminal regio : HRP (ARP38745 T100-HRP)

Nuclear factor (erythroid-derived 2) -like 2

NRF2, HEBP1, Nrf-2, IMDDHH

4780

Q16236

NP_006155

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human NFE2L2

NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other. NFE2L2 may be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995) .[supplied by OMIM].

BACH1; HDAC3; WAC; FBXW11; KEAP1; TNNT1; MAPK7; HDAC2; HDAC1; MAFF; MAFG; MAFK; MAP2K2; MAP2K1; MAPK9; MAPK8; AKT1; UBC; NQO1; BRCA1; AHR; CREB3; NFE2L3; ENC1; SIAH2; NFE2; ATF4; Pparg; SUMO1; SUMO2; RNF4; BPTF; RBMX; KPNA3; SUMO3; MYC; DYT10; Ube2e1; PGA

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

NFE2L2 is supported by BioGPS gene expression data to be expressed in A172

0.5 mg/ml

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

68kDa

Padmanabhan, B., et al., (2006) Mol. Cell 21 (5), 689-700

Wet Ice

605

NFE2L2

NFE2L2

Rabbit

Nuclear factor erythroid 2-related factor 2

NM_006164

KEKGENDKSLHLLKKQLSTLYLEVFSMLRDEDGKPYSPSEYSLQQTRDGN