NFKB2 Antilichaam - C-terminalgebied: FITC (ARP32043 P050-FITC)

Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

P52, p100, H2TF1, LYT10, CVID10, LYT-10, NF-kB2, p49/p100

4791

Q00653

NP_002493

Human, Rat, Cow, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human NFKB2

NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.

FBXW11; UBC; RELB; RELA; REL; NFKB1; CHUK; BCL3; SUMO1; NEDD8; TNFAIP3; BIRC2; EPS8; VCP; UBD; BRRF1; COMMD1; COMMD2; MAP3K14; BTRC; NFKB2; FBXW7; TSG101; IKBKG; SUMO2; DPF2; PSMD11; NFKBIZ; TNIP2; HDAC5; NFKBIB; HDAC4; USP2; NFKBIE; RPL6; IKBKB; TSC22D3

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

IHC, WB

Affinity Purified

0.5 mg/ml

Cow: 77%; Horse: 85%; Human: 100%; Pig: 77%; Rabbit: 92%; Rat: 77%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

97kDa

Xiao, G., et al., (2004) J. Biol. Chem. 279 (29), 30099-30105

Wet Ice

900

NFKB2

NFKB2

Rabbit

Nuclear factor NF-kappa-B p100 subunit

NM_002502

SDSDSDSEGPEKDTRSSFRGHTPLDLTCSTLVKTLLLNAAQNTMEPPL