NFKBIZ-antilichaam

This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS) . The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene.

64332

Q9BYH8

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human NFKBIZ (NP_113607.1) .

Unconjugated

Primary Antibodies

Apoptosis, Cell Cycle, Immunology, Innate Immunity, Transcription

Affinity purification

LO2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 68-90kDa

IgG

NFKBIZ

THP-1

Mouse kidney

Rat kidney

NFKB inhibitor zeta

Homo sapiens

IKBZ, INAP, MAIL, NF-kappa-B inhibitor zeta, I-kappa-B-zeta, IL-1 inducible nuclear ankyrin-repeat protein, Ikappa B-zeta variant 3, IkappaB-zeta, ikB-zeta, ikappaBzeta, molecule possessing ankyrin repeats induced by lipopolysaccharide, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta

WB, IF

Liquid