NG2-bindingspeptide

NG2 binding peptide is a short peptide that specifically recognizes NG2 proteoglycan and can be obtained by phage screening technology. NG2 binding peptide interacts with NG2 binding sites to achieve precise targeting of tumor angiogenesis in vitro and in vivo. NG2 binding peptide exhibits significant homing ability in wild-type tumor-bearing mice, but has no localization effect in NG2 knockout mice. Due to the tissue specificity of NG2 expression, NG2 binding peptide can be used in scenarios such as tumor targeted therapy, drug delivery, and molecular imaging diagnosis[1].

241478-23-9

12352209

Others

Others

Cancer

O=C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CO)C(NCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H](CCSC)C(N[C@@H](CC1=CNC=N1)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@H](O)C)N

C40H69N15O14S

1016.13

[1]Burg MA, et al. NG2 proteoglycan-binding peptides target tumor neovasculature. Cancer Res. 1999 Jun 15;59 (12) :2869-74.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P10989/

Peptides

No Development Reported