NGM-438
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
NGM-438 is a humanized IgG1 monoclonal antibody targeting LAIR1. NGM438 reversed collagen-induced immune suppression in myeloid cells and promoted anti-PD1 mAb-driven T cell responses in immune cell-based functional assays[1].
12352203
MMP
Metabolic Enzyme/Protease
Metabolism-protein/nucleotide metabolism
Cancer
99.74
(144.92 kDa)
[1]Sisi He, et al. Preclinical development of NGM438, a novel anti-LAIR1 antagonist monoclonal antibody for the treatment of collagen-rich solid tumors [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA) : AACR; Cancer Res 2022;82 (12_Suppl) :Abstract nr LB219.
Dry Ice
-80°C
http://file.medchemexpress.com/batch_PDF/HY-P991193/NGM-438-SDS-MedChemExpress.pdf
Inhibitory Antibodies
Phase 1
Beschrijving
NGM-438 is a humanized IgG1 monoclonal antibody targeting LAIR1. NGM438 reversed collagen-induced immune suppression in myeloid cells and promoted anti-PD1 mAb-
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