NHI-2
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
NHI-2 is a selective inhibitor of Lactate Dehydrogenase A (LDHA) – IC50 in vitro = 14.7 µM (NADH), 10.5 µM (Pyruvate) .1 NHI-2 has also shown cellular growth inhibitory effects against pancreatic cancer cells (PANC-1 cells IC50 = 22.2 µM normoxic and 4.0 µM hypoxic; LPC006 cells IC50 = 17.8 µM normoxic and 1.1 µM hypoxic) with increased efficacy in a cancer cells hypoxic environment.2 LDHA is a key enzyme involved in the Warburg effect and a cancer cells ability to survive in a hypoxic environment.
Unconjugated
Off-white solid
-20°C
Beschrijving
NHI-2 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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