NHLRC3 Polyklonale Antilichaam, PE-Cy5,5 Vervoeging

NHLRC3 contains 4 NHL repeats. The function of the NHLRC3 protein remains unknown. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.

DKFZp313M1221; DKFZp686E1140; NHL repeat containing 3; NHL repeat containing protein 3; NHLRC 3; NHLC3_HUMAN.

Human, Mouse, Rat

101-200/347

NHLRC3

PE-Cy5.5

KLH conjugated synthetic peptide derived from human NHLRC3

WB

Purified by Protein A.

488nm/694nm

1µg/µl

WB (WB=1:500-2000)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.