
NI-1201
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
NI-1201 is a monoclonal antibody that targets, in the human IL-6R sequence, the epitope recognized by 25F10 for mice. NI-1201 inhibits both IL-6 cis- and trans-signaling. NI-1201 targets site IIb of hIL-6R. NI-1201 inhibits gp130 binding to IL-6R[1].
TZLS-501
12352203
Interleukin Related
Immunology/Inflammation
Cancer-programmed cell death
Cancer
[1]Lacroix, M., et al., (2015) . Novel Insights into Interleukin 6 (IL-6) Cis- and Trans-signaling Pathways by Differentially Manipulating the Assembly of the IL-6 Signaling Complex. The Journal of biological chemistry, 290 (45), 26943–26953.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991602/
Inhibitory Antibodies
No Development Reported
Beschrijving
NI-1201 is a monoclonal antibody that targets, in the human IL-6R sequence, the epitope recognized by 25F10 for mice. NI-1201 inhibits both IL-6 cis- and trans-
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