NIRF (UHRF2) Mouse Monoclonal Antibody [Kloon ID: LBI4E10]

This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding. [provided by RefSeq, Feb 2012]

Carrier-free (BSA/glycerol-free) UHRF2 mouse monoclonal antibody, clone LBI4E10

NIRF; RNF107; TDRD23; URF2

Homo sapiens ubiquitin like with PHD and ring finger domains 2 (UHRF2), transcript variant 1, mRNA.

115426

Q96PU4

Unconjugated

WB 1:500~2000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Transcription Factors

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

UHRF2

https://www.ncbi.nlm.nih.gov/gene/?term=115426

https://www.uniprot.org/uniprot/Q96PU4