Nitisinon
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Inhibitor of 4-Hydroxyphenylpyruvate dioxygenase (HPPD; IC50 = 40 nM1 and 173 nM2) and is in clinical use for the treatment of hereditary tyrosinemia type 13. CD13+ cancer stem cells (CSCs) are dependent on aerobic metabolism of tyrosine - Nitisinone inhibition of tyrosine metabolism results in lowered availability of acetyl-CoA and fumarate for use in the citric acid cycle causing these CSCs to enter cell cycle, decreasing self-renewal, and making them more susceptible to chemotherapy.4 Nitisinone is a potential treatment option for cancers that rely on tyrosine metabolism.
Unconjugated
Beige solid
-20°C
Beschrijving
Nitisinon Beschikbaar in 50 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
CYP707A2 Antibody
GTR17947107
2 mg
SsDNA Assay Kit
12645ES60
100 Tests
Eco Alu MTP (HxD) 6x7=42 plates 35mm, 223x630x135mm
TE15336
1 Piece
Arachis hypogaea Lectin (PNA) - Biotinylated
21510020-1
5mg
Cellubrevin Antibody
MBS9436639-01
0.05 mL
Oxidative Stress Combo Assay Tissue Kit
EA-7008
1 Each
1,4- Dioxane Pure
1041330 500
500 mL
Benzonase ELISA Kit
EG23601S
96 Tests
Recent gezochte producten
Recombinant Deinococcus radiodurans Protein RecA (recA)
MBS1071366-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans Protein ApaG (apaG)
MBS1302345-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans Protein grpE (grpE)
MBS1306645-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans GTPase obg (obg)
MBS1312662-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans GTPase Era (era)
MBS1418228-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans GTPase Der (der)
MBS1445159-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans Enolase (eno)
MBS1455279-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans Protein nrdI (nrdI)
MBS1483359-01
0.05 mg (E-Coli)