Nkx3-1 Antilichaam - middelste regio : HRP (ARP37115 P050-HRP)

NK-3 transcription factor, locus 1 (Drosophila)

Ba, Bax, NKX, bag, NKX3., NKX3A, NKX3.1, Nkx-3., Nkx-3.1, bagpipe

18095

P97436

NP_035051

Mouse

The immunogen is a synthetic peptide directed towards the middle region of Mouse Nkx3-1

Nkx3-1 is a transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. It plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Nkx3-1 acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells and plays a role in the formation of minor salivary glands (particularly palatine and lingual glands) . It is essential for appropriate differentiation and secretory function of the bulbourethral gland.

Fem1b; SP2

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Mouse: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

27kDa

Wet Ice

237

NKX3-1

Nkx3-1

Rabbit

Homeobox protein Nkx-3.1

NM_010921

TPTEPESDAHFETYLLDCEHNPGDLASAPQVTKQPQKRSRAAFSHTQVIE