NLRP3/AIM2-IN-3
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1787787-60-3
C03572-5mg
NLRP3
Immunology & Inflammation
NLRP3/AIM2-IN-3 (compound 59) is a potent inhibitor with species-specific effects on NLRP3 and AIM2 inflammasome-mediated pyroptosis. It demonstrates potent inhibition of pyroptosis in THP-1 macrophages stimulated with LPS/nigericin, with an IC50 of 0.077 μM. It also disrupts the interaction between NLRP3 or AIM2 and the adaptor protein ASC, effectively preventing ASC oligomerization and blocking inflammasome assembly.
Beschrijving
NLRP3/AIM2-IN-3 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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