NME1 Antilichaam

This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

4830

P15531

Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 90 to the C-terminus of human NME1 (NP_000260.1) .

Unconjugated

Primary Antibodies

Apoptosis, Cancer, Cell Cycle, Neuroscience

Affinity purification

A-549

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 21kDa

IgG

NME1

MCF7

HeLa

HepG2

NME/NM23 nucleoside diphosphate kinase 1

Homo sapiens

NME1, AWD, GAAD, NB, NBS, NDPK-A, NDPKA, NM23, NM23-H1, non-metastatic cells 1, protein (NM23A) expressed in, NDP kinase A, OTTHUMP00000174772

WB, IHC, IF

Liquid