NMI Antilichaam - middengebied: Biotine (ARP35737_P050-Biotine)

N-myc (and STAT) interactor

9111

Q13287

NP_004679

Human, Mouse, Rat, Guinea Pig, Horse

The immunogen is a synthetic peptide directed towards the middle region of human NMI

NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has high expression in myeloid leukemia cell lines. NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

HSPA8; GCSH; GOLGA8EP; HDDC3; C9orf72; TXLNA; TXLNB; CNKSR3; LCA5L; C1orf216; SFR1; TUBA3E; MTMR9; COPS7B; BRMS1; KDM1A; POMZP3; HHLA3; EMILIN1; SNAPC5; MAD2L1BP; NMI; MTMR6; SCEL; TRAF5; UBC; PSMG3; OXR1; EXOSC4; TOLLIP; CYHR1; VPS26A; H1FX; NAA10; TBCD

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

0.5 mg/ml

Guinea Pig: 79%; Horse: 79%; Human: 100%; Mouse: 86%; Rat: 86%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

35kDa

Albihn, A., (2007) Int. J. Cancer 121 (8), 1821-1829

Wet Ice

307

NMI

NMI

Rabbit

N-myc-interactor

NM_004688

SFSKSRNGGGEVDRVDYDRQSGSAVITFVEIGVADKILKKKEYPLYINQT