Nogapendekin alfa (zijn label)

Nogapendekin alfa (his tag), a soluble protein subunit of a human interleukin (IL) -15 variant, is a superagonist of IL-15. Nogapendekin alfa (his tag) promotes the proliferation and viability of immune cells. Nogapendekin alfa (his tag) combines with Inbakicept at a ratio of 2:1, to form N-803 (Nogapendekin alfa inbakicept), an IL-15 cytokine antibody fusion protein. N-803 reduces tumor burden by activation of NK cells and CD8+ T cells[1].

1622189-43-8

IL-15N72D

12352203

Interleukin Related

Immunology/Inflammation

COVID-19-immunoregulation

Cancer; Inflammation/Immunology

98.62

10 mM in DMSO

[Nogapendekinalfa(histag)]

(13.91 kDa)

[1]Chen W, et al. ALT-803 in the treatment of non-muscle-invasive bladder cancer: Preclinical and clinical evidence and translational potential. Front Immunol. 2022 Nov 10;13:1040669.

Dry Ice

Store at -80°C for 2 years

http://file.medchemexpress.com/batch_PDF/HY-P99759/Nogapendekin-alfa-his-tag-SDS-MedChemExpress.pdf

Inhibitory Antibodies

No Development Reported

IL-15