Norfluoxetine (hydrochloride) (standaard)

Arecoline (hydrobromide) (Standard) is the analytical standard of Arecoline (hydrobromide) . This product is intended for research and analytical applications. Arecoline hydrobromide, a naturally occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress[1][2][3][4].

57226-68-3

12352005

5-HT Receptor; Calcium Channel; Drug Metabolite; Reference Standards

GPCR/G Protein; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Neurological Disease; Cardiovascular Disease

FC(F)(F)C1=CC=C(OC(C2=CC=CC=C2)CCN)C=C1.Cl

C16H17ClF3NO

331.76

[1]Valéria Kecskeméti, et al. Norfluoxetine and fluoxetine have similar anticonvulsant and Ca2+ channel blocking potencies. Brain Res Bull. 2005 Sep 30;67 (1-2) :126-32.|[2]Achraf Traboulsie, et al. T-type calcium channels are inhibited by fluoxetine and its metabolite norfluoxetine. Mol Pharmacol. 2006 Jun;69 (6) :1963-8.|[3]Hyeon-Cheol Jeong, et al. Prediction of Fluoxetine and Norfluoxetine Pharmacokinetic Profiles Using Physiologically Based Pharmacokinetic Modeling. Clin Pharmacol. 2021 Nov;61 (11) :1505-1513.|[4]D T Wong, et al. Norfluoxetine enantiomers as inhibitors of serotonin uptake in rat brain. Neuropsychopharmacology. 1993 Jun;8 (4) :337-44.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W011235R/

Reference Standards