Norharmine
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Norharmine is a Harmine analogue and an alkaloid. Norharmine is the inhibitors of MAO-A and DYRK1A. Norharmine has weak inhibitory activity against MAO-A and certain inhibitory activity against DYRK1A[1].
6253-19-6
12352005
H302-H315-H319-H335
DYRK; Monoamine Oxidase
Neuronal Signaling; Protein Tyrosine Kinase/RTK
Others
COC1=CC(NC2=C3C=CN=C2)=C3C=C1
C12H10N2O
198.22
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
[1]Wurzlbauer A, et al. How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition-The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine. Molecules. 2020 Dec 16;25 (24) :5962.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W067583/
Reference compound1
No Development Reported
DYRK1; MAO-A
Beschrijving
Norharmine is a Harmine analogue and an alkaloid. Norharmine is the inhibitors of MAO-A and DYRK1A. Norharmine has weak inhibitory activity against MAO-A and ce
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