Notch1 Antilichaam [mN1A] (PE)

The mN1A monoclonal antibody reacts with the intracellular domain of human and mouse Notch1 with high affinity for the activated intracellular form and lower affinity for the full length heterodimeric Notch1 forms. It does not react with Notch2,3, or 4 and does not cross-react with rat thymocytes. The neurogenic locus homolog protein 1 (Notch1) is a trasmembrane receptor that regulates cell fate decisions. It is expressed in CD4-CD8- and CD4-CD8+ thymocytes, and plays a role in the regulation of myelopoiesis and lymphopoiesis.

4851;18128

P46531; Q01705

Human, Mouse

MN1A

PE

Primary Antibodies

Stem Cell, Cell Cycle

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Mouse IgG1, kappa

The mN1A monoclonal antibody reacts with the intracellular domain of human and mouse Notch1 with high affinity for the activated intracellular form and lower affinity for the full length heterodimeric Notch1 forms.

NOTCH1

Notch 1

Homo sapiens; Mus musculus

HN1, AOS5, TAN1, AOVD1, NOTCH1

Flow

Liquid