NPM1 ALK F1174L Recombinant humaan actief eiwit Kinase
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
The NPM1-ALK protein contains the NPM1 oligomerization motif and the ALK catalytic domain, is constitutively activated through autophosphorylation, and mediates malignant cell transformation by activating downstream effectors including STAT3. NPM1 ALK F1174L Recombinant Human Active Protein Kinase is a recombinant NPM1 ALK F1174L protein that can be used to study NPM1 ALK F1174L-related functions[1].
12352211
Anaplastic lymphoma kinase (ALK)
Protein Tyrosine Kinase/RTK
Cancer
[NPM1ALKF1174LRecombinantHumanActiveProteinKinase]
[1]Andraos E, et al. NPM-ALK: A Driver of Lymphoma Pathogenesis and a Therapeutic Target. Cancers (Basel) . 2021 Jan 5;13 (1) :144.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-E70761/
Enzyme
No Development Reported
Beschrijving
The NPM1-ALK protein contains the NPM1 oligomerization motif and the ALK catalytic domain, is constitutively activated through autophosphorylation, and mediates
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