NQO1 Antilichaam - C-terminaal gebied: Biotine (ARP61164 P050-Biotine)

NAD (P) H dehydrogenase, quinone 1

DTD, QR1, DHQU, DIA4, NMOR1, NMORI

1728

P15559

NP_000894

Human, Rat, Cow, Dog, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human NQO1

This gene is a member of the NAD (P) H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD) . Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UBC; FOS; NEDD8; SUMO1; NFE2L2; PARP1; BAG3; ITGA4; FN1; RPS10P5; POLDIP3; YTHDF1; RPS19; LAMB1; TP53; STUB1; ING1; DNAJB1; HSPA1A; NQO1; HSPA4

Biotin

Polyclonal Antibody

WB

Affinity Purified

There is BioGPS gene expression data showing that NQO1 is expressed in 721_B

0.5 mg/ml

Cow: 86%; Dog: 79%; Human: 100%; Rabbit: 91%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

31kDa

Wet Ice

274

NQO1

NQO1

Rabbit

NAD (P) H dehydrogenase [quinone] 1

NM_000903

WKKRLENIWDETPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVG