Nr1h3 Antilichaam - C-terminaal gebied: Biotine (ARP32674_P050-Biotine)

Nuclear receptor subfamily 1, group H, member 3

Un, LXR, RLD1, Unr1, AU018371

22259

Q9Z0Y9

NP_038867

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit

Nr1h3 is an orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Nr1h3 plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.

Ncor1; Ppargc1b; Zfp111; Rxrg; Rxra; Ppargc1a; Ubc

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

50kDa

Wet Ice

445

NR1H3

Nr1h3

Rabbit

Oxysterols receptor LXR-alpha

NM_013839

LLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSINHPHDPLMFPRM