NR2C2 Antilichaam - N-terminaal gebied: Biotine (ARP45614 P050-Biotine)

Nuclear receptor subfamily 2, group C, member 2

TR4, TAK1

7182

P49116

NP_003289

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human NR2C2

Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996 [PubMed 8661150]) .[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

VPRBP; CUL4B; UBC; DDB1; KDM1A; NR2C2; HSP90AA1; JAZF1; TAB2; TRAF6; PELI1; PELI2; RBCK1; PDLIM7; TAB1; TRIM28; MTA1; HDAC3; NR2C1; RBBP4; HDAC1; DNMT1; CHD4; Cebpb; ITSN2; CD2AP; RXRB; NR2C2AP; PEBP1; HSP90AB1; CDC37; IKBKB; FKBP5; TRAF2; CHUK; HNF4A; AR

Biotin

Polyclonal Antibody

WB

Affinity Purified

NR2C2 is supported by BioGPS gene expression data to be expressed in 721_B

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

67kDa

Bouwmeester, T., (2004) Nat. Cell Biol. 6 (2), 97-105

Wet Ice

615

NR2C2

NR2C2

Rabbit

Nuclear receptor subfamily 2 group C member 2

NM_003298

INKHHRNRCQFCRLKKCLEMGMKMESVQSERKPFDVQREKPSNCAASTEK