NR3C2 Antilichaam - middengebied: Biotine (ARP45599 T100-Biotine)

Nuclear receptor subfamily 3, group C, member 2

MR, MCR, MLR, NR3C2VIT

4306

P08235

NP_000892

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human NR3C2

NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.

RABAC1; RXRA; HSP90AA1; ACSL1; UBC; SRC; PPP5C; PPID; FKBP5; FKBP4; STUB1; AIP; TRIM24; NRIP1; DNAJC7; CAND1; SUMO1; UBE2I; EIF3I; PROX1; PIAS1; PIAS3; HSPA4; PTGES3; AR; NR3C1; ACTA1; ACTG1

Biotin

Polyclonal Antibody

IHC, WB

NR3C2 is supported by BioGPS gene expression data to be expressed in A172

0.5 mg/ml

Cow: 83%; Guinea Pig: 75%; Horse: 86%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 100%; Rat: 92%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

107kDa

Liu, G., (2006) Biochem. Biophys. Res. Commun. 342 (4), 1291-1296

Wet Ice

984

NR3C2

NR3C2

Rabbit

Mineralocorticoid receptor

NM_000901

RRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPP