NR4A1 Antilichaam - middengebied: HRP (ARP45604 P050-HRP)

Nuclear receptor subfamily 4, group A, member 1

HMR, N10, TR3, NP10, GFRP1, NAK-1, NGFIB, NUR77

3164

P22736

NP_002126

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human NR4A1

NR4A1 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

KRTAP10-5; KRTAP10-1; LONRF1; PGBD1; BCL2L10; CDKN2D; BCL2A1; BCL2; TUBB4A; VASP; ANKIB1; CUTA; NFKB1; SMAD3; LSS; HADHA; GLUD1; GK; CPT1A; SERPING1; ABCC6; ABCC13; SOCS4; ABCG8; DIABLO; HCVgp1; ABCA5; CHEK2; SUGT1; PRDX4; PRDX6; CHD1L; ABCB11; ARHGEF5; U

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

Affinity Purified

0.5 mg/ml

Cow: 85%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

64kDa

Smith, A.G., (2008) J. Biol. Chem. 283 (18), 12564-12570

Wet Ice

598

NR4A1

NR4A1

Rabbit

Nuclear receptor subfamily 4 group A member 1

NM_002135

FQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANLLTSLVRAHL