NR5A1 Antilichaam - middengebied: FITC (ARP31834_P050-FITC)

Nuclear receptor subfamily 5, group A, member 1

ELP, SF1, FTZ1, POF7, SF-1, AD4BP, FTZF1, SPGF8, SRXX4, SRXY3, hSF-1

2516

Q13285

NP_004950

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

The immunogen is a synthetic peptide directed towards the middle region of human NR5A1

NR5A1 is an important regulator of steroidogeneisis which is present in human skin and its appendages. It plays a role in regulating p450scc expression with TReP-132 and CBP/p300. The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

NCK2; NR0B1; RAD54L2; THOC2; ALYREF; EIF4A3; DDX39B; UBC; BARD1; ELAVL1; TCF7L2; CTNNB1; CREBBP; CXXC1; PNRC2; SOX8; PIAS1; ZNF653; TRERF1; EDF1; GATA4; GTF2B; SOX2; SOX9; TBX19; NCOA1; NRIP1; PITX1; SMARCD3; PROX1; AR; SP1; NFYA; MAPK1; JUN; NFKB2

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

IHC, WB

Affinity Purified

NR5A1 is supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 92%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 79%; Rabbit: 85%; Rat: 92%; Sheep: 85%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

52kDa

Li, L.A., et al., (2004) J. Steroid Biochem. Mol. Biol. 91 (1-2), 11-20

Wet Ice

461

NR5A1

NR5A1

Rabbit

Steroidogenic factor 1

NM_004959

AVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGP