NR5A2 Antilichaam - N-terminaal gebied: Biotine (ARP38386 T100-Biotine)

Nuclear receptor subfamily 5, group A, member 2

B1F, CPF, FTF, B1F2, LRH1, LRH-1, FTZ-F1, hB1F-2, FTZ-F1beta

2494

O00482

NP_995582

Human, Rat, Cow, Guinea Pig, Pig, Sheep

The immunogen is a synthetic peptide directed towards the N terminal region of human NR5A2

NR5A2 binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. It may be responsable for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. It is a key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. It may also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.

NSD1; NCOA1; CREB1; UBE2I; RAD54L2; NR0B2; GPS2; ILF3; PNRC2; COPS5; PNRC1; BCKDK; NRIP1; SRC; NPPA; FTH1; ALB; SUMO1; PPARGC1A; POLR2D; EDF1; SMARCD3; PROX1; Ncoa3; Ptpn6; CTNNB1

Biotin

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 100%; Guinea Pig: 86%; Human: 100%; Pig: 92%; Rat: 93%; Sheep: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

61kDa

Lee, Y.K., (2006) J. Biol. Chem. 281 (12), 7850-7855

Wet Ice

541

NR5A2

NR5A2

Rabbit

Nuclear receptor subfamily 5 group A member 2

NM_205860

MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGY