NRXN1 Antilichaam / Neurexine 1 bèta

Neurexin 1 is primarily known for its role in the formation and maintenance of synapses, the connections between neurons that allow for communication in the brain. It acts as a cell adhesion molecule, helping to guide the development of synapses and ensuring proper signaling between neurons. Studies have shown that mutations in the NRXN1 gene can lead to disruptions in synaptic function, ultimately impacting brain development and function. These mutations have been associated with a variety of neurological disorders, including autism spectrum disorder, schizophrenia, and intellectual disabilities.

Western blot: 1:1000-1:2000

P58400

Human, Mouse, Rat

A portion of amino acids 77-110 from the human protein was used as the immunogen for this NRXN1 antibody.

WB

Antigen affinity

Antigen affinity purified

This NRXN1 antibody is available for research use only.

Store at 4°C for up to one month. For long term, aliquot the NRXN1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

In 1X PBS, pH 7.4, with 0.09% sodium azide

The stated application concentrations are suggested starting amounts. Titration of the NRXN1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Western blot testing of 1) human brain, 2) human cerebellum, 3) human U-87 MG, 4) mouse brain, 5) mouse Neuro-2a and 6) rat brain tissue lysate with FOXN1 antibody. Predicted molecular weight ~50 kDa.