NRXN3 Antilichaam

This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder.

9369

Q9HDB5; Q9Y4C0

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 373-432 of human NRXN3 (NP_620426.2) .

Unconjugated

Primary Antibodies

Cell Cycle, Neuroscience

Affinity purification

SGC-7901

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 140kDa

IgG

WB: 1:1000 - 1:2000

NRXN3

Mouse liver

Rat liver

Neurexin 3

Homo sapiens

NRXN3, neurexin 3, KIAA0743, MGC176711, neurexin III

WB

Liquid