NSC 57148
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
NSC 57148 is a selective Grb7 SH2 domain antagonist with an IC50 value of 1.1 μM. NSC 57148 reduces cancer cell proliferation and migration. NSC 57148 is promising for research of Grb7-overexpressing malignancies such as breast and pancreatic cancers[1].
4315-44-0
12352005
EGFR
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Cancer
O=C(C1=CC=C(C(NC2=CC=C(C3=NC(CN3)C)C=C2)=O)C=C1)NC4=CC=C(C5=NC(CN5)C)C=C4.Cl.Cl
C28H30Cl2N6O2
553.48
[1]Ambaye ND, et al. The discovery of phenylbenzamide derivatives as Grb7-based antitumor agents. ChemMedChem. 2013 Feb;8 (2) :280-8.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-180498/
Reference compound1
No Development Reported
Beschrijving
NSC 57148 is a selective Grb7 SH2 domain antagonist with an IC50 value of 1.1 μM. NSC 57148 reduces cancer cell proliferation and migration. NSC 57148 is promis
Specificaties
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