NSC405020
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Membrane type-1 matrix metalloproteinase (MMP14 or MT1-MMP) inhibitor that prevents homodimerization and inhibits MMP14’s protumorigenic activity in vivo. (IC50 > 100 μM) . Inhibition is via interaction with the hemopexin domain (PEX) of MMP14. NSC-405020 does not interfere with the catalytic activity of MT1-MMP or MMP-2. Suppresses bone erosion in a c-Fos-deficient mouse model.2 Decreases arsenic-mediated invasion of human squamous cell carcinoma HSC5 cells.3
Unconjugated
White solid
RT
Beschrijving
NSC405020 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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