NSC47924
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
A potent inhibitor of the Leucine-rich repeat protein phosphatase (PHLPP) an enzyme which is a negative regulator of Akt and PKC (IC50=4 M) .1 Increases AKT signaling in cells and prevents apoptosis. Also inhibits the 67 kDa laminin receptor (LR) interaction with laminin (LM) and selectively blocks LR-293 cell adhesion to LM IC50=19.35 M) impairing cell migration and invasion.2 Affects 37/67 kDa LR cell surface localization and interaction with cellular prion protein.3
Unconjugated
Yellow solid
-20°C
Beschrijving
NSC47924 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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