Gecertificeerd

NT-4

Name: NT-4
Brand: Genprice.nl
SKU: 24356690
Price: 1441.61 EUR
Availability: InStock

Catalog #: 100-087-L100

Maat: 100 µg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%

BTW niet inbegrepen

Gratis verzending vanaf €100

Aantal:

Technische Specificaties

Description

NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues) .

Synonyms

NTF4; NT4; NT5; NT-4; NT-5; NTF5; GLC10; GLC1O; NT-4/5

NCBI Gene ID

4909

UniProt

P34130

Accession Number

NP_006170.1

Accession Number mRNA

NM_006179.4

Chromosomal Location

19q13.3

Reactivity

Human

Cross Reactivity

Rat, Frog, Human, Mouse

Sequence

GVSETAPASR RGELAVCDAV SGWVTDRRTA VDLRGREVEV LGEVPAAGGS PLRQYFFETR CKADNAEEGG PGAGGGGCRG VDRRHWVSEC KAKQSYVRAL TADAQGRVGW RWIRIDTACV CTLLSRTGRA

Endotoxin

< 0.1 ng/µg of protein (< 1EU/µg)

Purity

> 98% by SDS-PAGE & HPLC analyses

Bioactivity

Determined by its ability to bind recombinant human TrkB Fc Chimera in a functional ELISA.

Length

130

Form

Lyophilized

Molecular Weight

14 kDa

Host or Source

E. coli

Beschrijving

NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume sta

Specificaties

ProductnaamNT-4

Categorie

Beschikbare grootte100 µg

Catalogusnummer100-087-L100

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