NTRK1 Antilichaam

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

4914

P04629

Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 700 to the C-terminus of human NTRK1 (NP_002520.2) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Growth Factors, Neuroscience, Signal Transduction

Affinity purification

Mouse brain

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 140kDa

IgG

NTRK1

Rat brain

Neurotrophic tyrosine kinase, receptor, type 1

Homo sapiens

NTRK1, Oncogene TRK, TrkA/NGF receptor, Tropomyosin-related kinase A, TRK, TRK1, Tyrosine kinase receptor, Tyrosine kinase receptor A, gp140trk, MTC, p140-TrkA, Trk-A, TRKA

WB, IHC

Liquid