NTRK3 Antilichaam

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.

4916

Q16288

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human NTRK3 (NP_001007157.1) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Growth Factors, Neuroscience, Signal Transduction

Affinity purification

A-549

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 115kDa

IgG

NTRK3

HepG2

Mouse liver

NT-3 growth factor receptor

Homo sapiens

NT-3 growth factor receptor, GP145-TrkC, Trk-C, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase, NTRK3, TRKC

WB, IHC

Liquid