Nucleaire receptor NR4A1 (fosfo Ser351) Antilichaam

Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.

3164

P22736

NP_002126.2

Human, Mouse, Rat

Nuclear Receptor NR4A1 (phospho Ser351) antibody was raised against a peptide sequence around phosphorylation site of Serine351 (L-P-S (p) -K-P) derived from Human Nuclear Receptor NR4A1.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

64 kDa

IgG

The antibody detects endogenous levels of Nuclear Receptor NR4A1 only when phosphorylated at serine 351

NR4A1

Nuclear receptor subfamily 4, group A, member 1

Homo sapiens

Nakai A., Mol. Endocrinol. 4:1438-1443 (1990) .

Chang C., J. Steroid Biochem. 34:391-395 (1989) .

Bondy G.P., Cell Growth Differ. 2:203-208 (1991)

NGFIB, GFRP1, HMR, NR4A1, NAK1

IHC

27894346

Liquid