NUMB Antilichaam - middengebied HRP (ARP59434 P050-HRP)

Numb homolog (Drosophila)

S171, C14orf41, c14_5527

8650

P49757-4

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of Human NUMB

The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene.

TP53; PRKCA; PRKCZ; PRKCE; PRKCB; UBC; SIAH1; RPL3; EGFR; NOTCH1; MDM2; APP; Trp53; Jun; EPS15; Lnx1; ITCH; GLI1; LNX2; AP2A2; PRKCH; DPYSL2; AP2A1; ITGB2; L1CAM; PRKCG; PRKCD; ITGB3; ITGB5; Eps15l1; RALBP1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 83%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

64kDa

Wet Ice

592

NUMB

NUMB

Rabbit

Protein numb homolog

VGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQG