NUP50 Antilichaam - C-terminaal gebied: Biotine (ARP52288_P050-Biotine)

Nucleoporin 50kDa

NPAP60, NPAP60L

10762

Q9UKX7

NP_009103

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Yeast

The immunogen is a synthetic peptide directed towards the C terminal region of human NUP50

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP50 is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import.The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene.

KPNA5; KPNA4; KPNA3; KPNA2; KPNA1; KPNA6; UBC; KIAA1033; SART3; TTI1; TSC22D1; IKBKAP; KIF5B; EPB41L1; ACACA; SRPK2; LMNA; HDAC6; NPM1; UBAP2; TOR1AIP1; NUP153; APP; CUL3; Mki67; Kifc5b; SLX4; KPNB1; XPO1; RAN; CDKN1B; IPO13

Biotin

Polyclonal Antibody

IF, WB

Affinity Purified

There is BioGPS gene expression data showing that NUP50 is expressed in HepG2 NUP50 is supported by BioGPS gene expression data to be expressed in HeLa

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 85%; Horse: 100%; Human: 100%; Mouse: 91%; Pig: 100%; Rabbit: 100%; Rat: 92%; Yeast: 80%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

50kDa

Olsen, J.V., (2006) Cell 127 (3), 635-648

Wet Ice

468

NUP50

NUP50

Rabbit

Nuclear pore complex protein Nup50

NM_007172

TTQSKPVSSPFPTKPLEGQAEGDSGECKGGDEEENDEPPKVVVTEVKEED